IJMS | Free Full-Text | CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis
Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia | Journal of Hematology & Oncology | Full Text
The Mll–AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis | The EMBO Journal
Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth
MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors | Nature Communications
Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model | Leukemia
MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome - ScienceDirect
Frontiers | Murine Models of Acute Myeloid Leukemia
Modeling the Initiation and Progression of Human Acute Leukemia in Mice | Science
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia - ScienceDirect
Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9 - eBioMedicine
Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL -AF9-Driven AML - ScienceDirect
Iron metabolism in the MLL-AF9 AML mouse model. (A) MLL-AF9 1 AML cells... | Download Scientific Diagram
An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells | PLOS ONE
IJMS | Free Full-Text | Murine Models of Acute Myeloid Leukaemia
Integrated transcriptomic and epigenetic data analysis identifiesaberrant expression of genes in acute myeloid leukemia with MLL‑AF9 translocation Corrigendum in /10.3892/mmr.2021.12295
An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells | PLOS ONE
JCI - MLL-AF9– and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C
Iron metabolism in the MLL-AF9 AML mouse model. (A) MLL-AF9 + AML... | Download Scientific Diagram
P2X7 promotes the progression of MLL-AF9 induced acute myeloid leukemia by upregulation of Pbx3 | Haematologica
MLL-AF9 leukemia is delayed in Mbnl1 knockout mice a Scheme of mouse... | Download Scientific Diagram
Histone H3K36me2-specific methyltransferase ASH1L is required for the MLL- AF9-induced leukemogenesis | bioRxiv
Cancers | Free Full-Text | Pathways, Processes, and Candidate Drugs Associated with a Hoxa Cluster-Dependency Model of Leukemia
